4HS3
Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34
Summary for 4HS3
Entry DOI | 10.2210/pdb4hs3/pdb |
Descriptor | H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Envelope glycoprotein, ... (6 entities in total) |
Functional Keywords | mhc class i, antigen presentation, antigen processing, peptide binding, igg, mhc, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01901 Secreted: P01887 |
Total number of polymer chains | 3 |
Total formula weight | 44680.14 |
Authors | Uchtenhagen, H.,Boulanger, B.,Hein, Z.,Abualrous, E.T.,Zacharias, M.,Werner, J.,Elliott, T.,Springer, S.,Achour, A. (deposition date: 2012-10-29, release date: 2014-05-07, Last modification date: 2023-09-20) |
Primary citation | Hein, Z.,Uchtenhagen, H.,Abualrous, E.T.,Saini, S.K.,Janen, L.,Van Hateren, A.,Wiek, C.,Hanenberg, H.,Momburg, F.,Achour, A.,Elliott, T.,Springer, S.,Boulanger, D. Peptide-independent stabilization of MHC class I molecules breaches cellular quality control. J.Cell.Sci., 127:2885-2897, 2014 Cited by PubMed: 24806963DOI: 10.1242/jcs.145334 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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