4HPG

Crystal structure of a glycosylated beta-1,3-glucanase (HEV B 2), an allergen from Hevea brasiliensis

Replaces:  3EM5

Summary for 4HPG

• Entry DOI: 10.2210/pdb4hpg/pdb
• Descriptor: Beta-1,3-glucanase, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: allergen, glycoprotein, glycoside hydrolase, gh17 family, pathogenesis-related class-2 protein, tim barrel, glycosidase hydrolase, carbohydrate/sugar binding, glycosylation, pyroglutamic acid (n-terminal residue), latex, hydrolase
• Biological source: Hevea brasiliensis (Para rubber tree,jebe,rubbertree,siringa)
• Total number of polymer chains: 4
• Total formula weight: 142444.33

Authors

Rodriguez-Romero, A.,Hernandez-Santoyo, A. (deposition date: 2012-10-23, release date: 2013-11-27, Last modification date: 2023-09-20)

• Primary citation: Rodriguez-Romero, A.,Hernandez-Santoyo, A.,Fuentes-Silva, D.,Palomares, L.A.,Munoz-Cruz, S.,Yepez-Mulia, L.,Orozco-Martinez, S.; Structural analysis of the endogenous glycoallergen Hev b 2 (endo-beta-1,3-glucanase) from Hevea brasiliensis and its recognition by human basophils.; Acta Crystallogr.,Sect.D, 70:329-341, 2014; PubMed: 24531467; DOI: 10.1107/S1399004713027673

Experimental method

X-RAY DIFFRACTION (2.5364 Å)