4HNI

crystal structure of ck1e in complex with PF4800567

Summary for 4HNI

Entry DOI	10.2210/pdb4hni/pdb
Related	4HNK 4HOK
Descriptor	Casein kinase I isoform epsilon, 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, SULFATE ION, ... (4 entities in total)
Functional Keywords	ck1e, kinase, inhibitor, pf4800567, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	70215.41
Authors	Huang, X.,Long, A.M.,Zhao, H. (deposition date: 2012-10-19, release date: 2012-11-14, Last modification date: 2024-02-28)
Primary citation	Long, A.M.,Zhao, H.,Huang, X. Structural basis for the potent and selective inhibition of casein kinase 1 epsilon. J.Med.Chem., 55:10307-10311, 2012 Cited by PubMed: 23106386 DOI: 10.1021/jm301336n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.74 Å)

Structure validation