4HNE
Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP
Summary for 4HNE
Entry DOI | 10.2210/pdb4hne/pdb |
Related | 4HND |
Descriptor | Phosphatidylinositol 4-kinase type 2-alpha, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | pi3k/pi4k kinase, lipid kinase, atp binding, palmitoylation, membrane anchoring, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9BTU6 |
Total number of polymer chains | 2 |
Total formula weight | 88504.16 |
Authors | |
Primary citation | Zhou, Q.,Li, J.,Yu, H.,Zhai, Y.,Gao, Z.,Liu, Y.,Pang, X.,Zhang, L.,Schulten, K.,Sun, F.,Chen, C. Molecular insights into the membrane-associated phosphatidylinositol 4-kinase II alpha. Nat Commun, 5:3552-3552, 2014 Cited by PubMed: 24675427DOI: 10.1038/ncomms4552 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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