4HLT

Crystal structure of ferric E32V Pirin

Summary for 4HLT

Entry DOI	10.2210/pdb4hlt/pdb
Related	4ERO 4EWA 4EWD 4EWE 4GUL
Descriptor	Pirin, FE (II) ION (3 entities in total)
Functional Keywords	beta sandwich, cupin, iron, metal binding protein, transcription cofactor activity, protein binding, nucleus, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus : O00625
Total number of polymer chains	1
Total formula weight	31997.01
Authors	Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,Serrano, V.,Liu, A. (deposition date: 2012-10-17, release date: 2013-05-29, Last modification date: 2023-09-20)
Primary citation	Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A. Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013 Cited by PubMed: 23716661 DOI: 10.1073/pnas.1221743110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation