4HLS

Crystal structure of mutant rabbit PRP 121-230 (S170N)

Summary for 4HLS

• Entry DOI: 10.2210/pdb4hls/pdb
• Related: 4HMM 4HMR
• Descriptor: Major prion protein, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: prp, prion, membrane, membrane protein
• Biological source: Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): Q95211
• Total number of polymer chains: 2
• Total formula weight: 31019.04

Authors

Sweeting, B.,Chakrabartty, A.,Pai, E.F. (deposition date: 2012-10-17, release date: 2013-05-15, Last modification date: 2023-09-20)

• Primary citation: Sweeting, B.,Brown, E.,Khan, M.Q.,Chakrabartty, A.,Pai, E.F.; N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins.; Plos One, 8:e63047-e63047, 2013; PubMed: 23675452; DOI: 10.1371/journal.pone.0063047

Experimental method

X-RAY DIFFRACTION (1.45 Å)