4HKQ

XMRV reverse transcriptase in complex with RNA/DNA hybrid

4HKQ の概要

• エントリーDOI: 10.2210/pdb4hkq/pdb
• 分子名称: Reverse transcriptase/ribonuclease H p80, RNA (5'-R(*AP*AP*CP*AP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*CP*AP*U)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*A*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), ... (4 entities in total)
• 機能のキーワード: protein-dna-rna complex, reverse transcription, transcription-rna-dna complex, transcription/rna/dna
• 由来する生物種: Xenotropic MuLV-related virus (XMRV); 詳細
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential): A1Z651
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 90967.72

構造登録者

Nowak, E.,Potrzebowski, W.,Konarev, P.V.,Rausch, J.W.,Bona, M.K.,Svergun, D.I.,Bujnicki, J.M.,Le Grice, S.F.J.,Nowotny, M. (登録日: 2012-10-15, 公開日: 2013-02-20, 最終更新日: 2023-11-08)

• 主引用文献: Nowak, E.,Potrzebowski, W.,Konarev, P.V.,Rausch, J.W.,Bona, M.K.,Svergun, D.I.,Bujnicki, J.M.,Le Grice, S.F.,Nowotny, M.; Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid; Nucleic Acids Res., 41:3874-3887, 2013; PubMed: 23382176; DOI: 10.1093/nar/gkt053

実験手法

X-RAY DIFFRACTION (3.04 Å)