4HKA

Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase in complex with HEME

4HKA の概要

• エントリーDOI: 10.2210/pdb4hka/pdb
• 分子名称: Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• 機能のキーワード: kynurenine pathway, catalytic mechanism, regulatory mechanism, oxidoreductase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43978.21

構造登録者

Huang, W.,Ding, J. (登録日: 2012-10-15, 公開日: 2013-03-27, 最終更新日: 2024-02-28)

• 主引用文献: Huang, W.,Gong, Z.,Li, J.,Ding, J.; Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism.; J.Struct.Biol., 181:291-299, 2013; PubMed: 23333332; DOI: 10.1016/j.jsb.2013.01.002

実験手法

X-RAY DIFFRACTION (2.7 Å)