4HGP

Crystal Structure of 2-keto-3-deoxyoctulosonate 8-phosphate phosphohydrolase from Haemophilus influenzae in complex with transition state mimic

Summary for 4HGP

Entry DOI	10.2210/pdb4hgp/pdb
Related	1k1e 4HGN 4HGO 4HGQ 4HGR
Descriptor	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC, MAGNESIUM ION, oxido(dioxo)vanadium, ... (5 entities in total)
Functional Keywords	rossmann fold, phosphohydroylase, hydrolase
Biological source	Haemophilus influenzae
Total number of polymer chains	1
Total formula weight	19816.72
Authors	Daughtry, K.D.,Allen, K.N. (deposition date: 2012-10-08, release date: 2013-08-21, Last modification date: 2023-09-20)
Primary citation	Daughtry, K.D.,Huang, H.,Malashkevich, V.,Patskovsky, Y.,Liu, W.,Ramagopal, U.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Dunaway-Mariano, D.,Allen, K.N. Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis. Biochemistry, 52:5372-5386, 2013 Cited by PubMed: 23848398 DOI: 10.1021/bi400659k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation