4HGC
Crystal structure of bovine trypsin complexed with sfti-1 analog containing a peptoid residue at position p1
Summary for 4HGC
Entry DOI | 10.2210/pdb4hgc/pdb |
Related | 1SFI 3MI4 3P8F |
Related PRD ID | PRD_001025 |
Descriptor | Cationic trypsin, Trypsin inhibitor 1, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase, serine protease, cyclic peptide, peptoid, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cow) More |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 2 |
Total formula weight | 25647.85 |
Authors | Krzywda, S.,Jaskolski, M.,Rolka, K.,Stawikowski, M. (deposition date: 2012-10-08, release date: 2013-10-09, Last modification date: 2023-11-15) |
Primary citation | Krzywda, S.,Jaskolski, M.,Rolka, K.,Stawikowski, M.J. Structure of a proteolytically resistant analogue of (NLys)(5)SFTI-1 in complex with trypsin: evidence for the direct participation of the Ser214 carbonyl group in serine protease-mediated proteolysis. Acta Crystallogr.,Sect.D, 70:668-675, 2014 Cited by PubMed: 24598736DOI: 10.1107/S1399004713032252 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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