4HG3

Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with alpha-ketoglutarate

Summary for 4HG3

• Entry DOI: 10.2210/pdb4hg3/pdb
• Related: 4H5U 4HG5 4HGD
• Descriptor: Probable hydrolase NIT2, 2-OXOGLUTARIC ACID, GLYCEROL, ... (5 entities in total)
• Functional Keywords: nitrilase superfamily, omega-amidase, hydrolase
• Biological source: Saccharomyces cerevisiae (Baker's yeast)
• Total number of polymer chains: 4
• Total formula weight: 156192.05

Authors

Liu, H.,Qiu, X.,Zhang, M.,Gao, Y.,Niu, L.,Teng, M. (deposition date: 2012-10-06, release date: 2013-07-31, Last modification date: 2023-11-08)

• Primary citation: Liu, H.,Gao, Y.,Zhang, M.,Qiu, X.,Cooper, A.J.L.,Niu, L.,Teng, M.; Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2; Acta Crystallogr.,Sect.D, 69:1470-1481, 2013; PubMed: 23897470; DOI: 10.1107/S0907444913009347

Experimental method

X-RAY DIFFRACTION (1.93 Å)