4HD0

Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair

4HD0 の概要

• エントリーDOI: 10.2210/pdb4hd0/pdb
• 分子名称: DNA double-strand break repair protein Mre11, MANGANESE (II) ION (3 entities in total)
• 機能のキーワード: nuclease enzyme, double-strand break repair, rad50, nbs1, mutation l204r, dna binding protein
• 由来する生物種: Pyrococcus furiosus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79822.74

構造登録者

Limbo, O.,Moiani, D.,Kertokalio, A.,Wyman, C.,Tainer, J.A.,Russell, P. (登録日: 2012-10-01, 公開日: 2012-10-31, 最終更新日: 2024-02-28)

• 主引用文献: Limbo, O.,Moiani, D.,Kertokalio, A.,Wyman, C.,Tainer, J.A.,Russell, P.; Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.; Nucleic Acids Res., 40:11435-11449, 2012; PubMed: 23080121; DOI: 10.1093/nar/gks954

実験手法

X-RAY DIFFRACTION (2.3 Å)