4H8E
Structure of S. aureus undecaprenyl diphosphate synthase in complex with FPP and sulfate
Summary for 4H8E
Entry DOI | 10.2210/pdb4h8e/pdb |
Related | 4H2J 4H2M 4H2O 4H38 4H3A 4H3C |
Descriptor | Undecaprenyl pyrophosphate synthase, MAGNESIUM ION, FARNESYL DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | alpha-helix, prenyl transferase, cell wall biosynthesis, farnesyl diphosphate binding, isopentenyl diphosphate binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Staphylococcus aureus subsp. aureus |
Total number of polymer chains | 1 |
Total formula weight | 30404.89 |
Authors | Zhu, W.,Oldfield, E. (deposition date: 2012-09-22, release date: 2012-12-19, Last modification date: 2024-02-28) |
Primary citation | Zhu, W.,Zhang, Y.,Sinko, W.,Hensler, M.E.,Olson, J.,Molohon, K.J.,Lindert, S.,Cao, R.,Li, K.,Wang, K.,Wang, Y.,Liu, Y.L.,Sankovsky, A.,de Oliveira, C.A.,Mitchell, D.A.,Nizet, V.,McCammon, J.A.,Oldfield, E. Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110:123-128, 2013 Cited by PubMed: 23248302DOI: 10.1073/pnas.1219899110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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