4GWN

Crystal structure of human mature meprin beta

4GWN の概要

• エントリーDOI: 10.2210/pdb4gwn/pdb
• 関連するPDBエントリー: 4GWM
• 分子名称: Meprin A subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: multidomain structure, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein: Q16820
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 67819.65

構造登録者

Arolas, J.L.,Broder, C.,Jefferson, T.,Guevara, T.,Sterchi, E.E.,Bode, W.,Stocker, W.,Becker-Pauly, C.,Gomis-Ruth, F.X. (登録日: 2012-09-03, 公開日: 2012-09-19, 最終更新日: 2023-11-08)

• 主引用文献: Arolas, J.L.,Broder, C.,Jefferson, T.,Guevara, T.,Sterchi, E.E.,Bode, W.,Stocker, W.,Becker-Pauly, C.,Gomis-Ruth, F.X.; Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane; Proc.Natl.Acad.Sci.USA, 109:16131-16136, 2012; PubMed: 22988105; DOI: 10.1073/pnas.1211076109

実験手法