4GUX

Crystal structure of trypsin:MCoTi-II complex

Summary for 4GUX

Entry DOI	10.2210/pdb4gux/pdb
Related PRD ID	PRD_000750
Descriptor	Cationic trypsin, Trypsin inhibitor 2, CALCIUM ION, ... (5 entities in total)
Functional Keywords	cyclotide, cyclic peptide, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (bovine,cow,domestic cattle,domestic cow) More
Cellular location	Secreted, extracellular space: P00760 Secreted: P82409
Total number of polymer chains	6
Total formula weight	88106.03
Authors	King, G.J.,Daly, N.L.,Thorstholm, L.,Greenwood, K.P.,Rosengren, K.J.,Heras, B.,Craik, D.J.,Martin, J.L. (deposition date: 2012-08-30, release date: 2013-09-04, Last modification date: 2023-11-08)
Primary citation	Daly, N.L.,Thorstholm, L.,Greenwood, K.P.,King, G.J.,Rosengren, K.J.,Heras, B.,Martin, J.L.,Craik, D.J. Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor J.Biol.Chem., 288:36141-36148, 2013 Cited by PubMed: 24169696 DOI: 10.1074/jbc.M113.528240 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.803 Å)

Structure validation