4GRM

The crystal structure of the high affinity TCR A6

Summary for 4GRM

• Entry DOI: 10.2210/pdb4grm/pdb
• Related: 3QH3
• Descriptor: A6 alpha chain, A6 beta chain (3 entities in total)
• Functional Keywords: high-affinity tcr, c134 modification, tax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 97696.00

Authors

Borbulevych, O.Y.,Scott, D.R.,Baker, B.M. (deposition date: 2012-08-25, release date: 2013-07-10, Last modification date: 2018-01-24)

• Primary citation: Cole, D.K.,Sami, M.,Scott, D.R.,Rizkallah, P.J.,Borbulevych, O.Y.,Todorov, P.T.,Moysey, R.K.,Jakobsen, B.K.,Boulter, J.M.,Baker, B.M.,Li, Y.I.; Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode.; Front Immunol, 4:168-168, 2013; PubMed: 23805144; DOI: 10.3389/fimmu.2013.00168

Experimental method

X-RAY DIFFRACTION (2 Å)