4GNG

Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide

4GNG の概要

• エントリーDOI: 10.2210/pdb4gng/pdb
• 関連するPDBエントリー: 4GND 4GNE 4GNF
• 分子名称: Histone-lysine N-methyltransferase NSD3, Histone H3.3, ZINC ION, ... (5 entities in total)
• 機能のキーワード: zinc finger, transcription, histone, lysine methyaltion, nuclear protein, transferase-nuclear protein complex, transferase/nuclear protein
• 由来する生物種: Homo sapiens; 詳細
• 細胞内の位置: Nucleus (By similarity): Q9BZ95; Nucleus: P84243
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28132.89

構造登録者

Li, F.,He, C.,Wu, J.,Shi, Y. (登録日: 2012-08-17, 公開日: 2013-01-02, 最終更新日: 2023-11-08)

• 主引用文献: He, C.,Li, F.,Zhang, J.,Wu, J.,Shi, Y.; The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.; J.Biol.Chem., 288:4692-4703, 2013; PubMed: 23269674; DOI: 10.1074/jbc.M112.426148

実験手法

X-RAY DIFFRACTION (1.73 Å)