4GLY
Human urokinase-type plasminogen activator uPA in complex with the two-disulfide bridge peptide UK504
Summary for 4GLY
Entry DOI | 10.2210/pdb4gly/pdb |
Related | 3QN7 |
Related PRD ID | PRD_001039 |
Descriptor | Urokinase-type plasminogen activator, BICYCLIC PEPTIDE INHIBITOR UK504, SULFATE ION, ... (8 entities in total) |
Functional Keywords | serine protease, chymotrypsin fold, urokinase-type plasminogen activator, bicyclic peptide inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00749 |
Total number of polymer chains | 2 |
Total formula weight | 29962.20 |
Authors | Buth, S.A.,Leiman, P.G.,Chen, S.,Heinis, C. (deposition date: 2012-08-15, release date: 2013-05-15, Last modification date: 2023-09-13) |
Primary citation | Chen, S.,Rentero Rebollo, I.,Buth, S.A.,Morales-Sanfrutos, J.,Touati, J.,Leiman, P.G.,Heinis, C. Bicyclic Peptide Ligands Pulled out of Cysteine-Rich Peptide Libraries. J.Am.Chem.Soc., 135:6562-6569, 2013 Cited by PubMed: 23560397DOI: 10.1021/ja400461h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.518 Å) |
Structure validation
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