4GH1
tRNA Guanine Transglycosylase in complex with morpholine substituted lin-benzohypoxanthine inhibitor
Summary for 4GH1
Entry DOI | 10.2210/pdb4gh1/pdb |
Related | 3S1G 3SM0 3TLL 4GG9 4GH3 4GHR 4GI4 |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 4-{2-[(cyclohexylmethyl)amino]ethyl}-2-{[2-(morpholin-4-yl)ethyl]amino}-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total) |
Functional Keywords | tim barrel, glycosyltransferase, queuosine, biosynthesis, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43536.79 |
Authors | Immekus, F.,Klebe, G. (deposition date: 2012-08-07, release date: 2013-09-04, Last modification date: 2023-09-13) |
Primary citation | Immekus, F.,Barandun, L.J.,Diederich, F.,Klebe, G. Two-armed benzopurine inhibitors of TGT To be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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