4GGF
Crystal structure of Mn2+ bound calprotectin
Summary for 4GGF
Entry DOI | 10.2210/pdb4ggf/pdb |
Descriptor | Protein S100-A8, Protein S100-A9, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | s100, ef-hand, antimicrobial protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P05109 P06702 |
Total number of polymer chains | 8 |
Total formula weight | 98047.93 |
Authors | Damo, S.M.,Fritz, G. (deposition date: 2012-08-06, release date: 2013-02-20, Last modification date: 2023-09-13) |
Primary citation | Damo, S.M.,Kehl-Fie, T.E.,Sugitani, N.,Holt, M.E.,Rathi, S.,Murphy, W.J.,Zhang, Y.,Betz, C.,Hench, L.,Fritz, G.,Skaar, E.P.,Chazin, W.J. Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc.Natl.Acad.Sci.USA, 110:3841-3846, 2013 Cited by PubMed: 23431180DOI: 10.1073/pnas.1220341110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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