4G8K
Intact sensor domain of human RNase L in the inactive signaling state
Summary for 4G8K
Entry DOI | 10.2210/pdb4g8k/pdb |
Related | 4G8L |
Descriptor | 2-5A-dependent ribonuclease (2 entities in total) |
Functional Keywords | ankyrin-repeat domain, single-stranded rna, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q05823 |
Total number of polymer chains | 2 |
Total formula weight | 74288.61 |
Authors | Han, Y.,Whitney, G.,Donovan, J.,Korennykh, A. (deposition date: 2012-07-23, release date: 2012-10-31, Last modification date: 2023-09-13) |
Primary citation | Han, Y.,Whitney, G.,Donovan, J.,Korennykh, A. Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes. Cell Rep, 2:902-913, 2012 Cited by PubMed: 23084743DOI: 10.1016/j.celrep.2012.09.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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