4G6M
Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab
Summary for 4G6M
| Entry DOI | 10.2210/pdb4g6m/pdb |
| Related | 4G5Z 4G6J 4G6K |
| Descriptor | Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment, ... (4 entities in total) |
| Functional Keywords | immunoglobulin fold, immune system, interleukine-1beta |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm, cytosol : P01584 |
| Total number of polymer chains | 3 |
| Total formula weight | 64071.03 |
| Authors | Blech, M.,Hoerer, S. (deposition date: 2012-07-19, release date: 2012-12-19, Last modification date: 2023-09-13) |
| Primary citation | Blech, M.,Peter, D.,Fischer, P.,Bauer, M.M.,Hafner, M.,Zeeb, M.,Nar, H. Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab J.Mol.Biol., 425:94-111, 2013 Cited by PubMed: 23041424DOI: 10.1016/j.jmb.2012.09.021 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
Download full validation report
