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4G6M

Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Interleukin-1 betapolymer15017150.61UniProt (P01584)
Pfam (PF00340)
Homo sapiens (human)IL-1 beta, Catabolin
2B
(H)
heavy chain of gevokizumab antibody binding fragmentpolymer22023420.21homo Sapiens Mus musculus (human mouse)
3C
(L)
light chain of gevokizumab antibody binding fragmentpolymer21323500.21homo Sapiens Mus musculus (human mouse)
4D, E, F
(A, H, L)
waterwater18.0442Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight64071.0
All*Total formula weight64071.0
*Water molecules are not included.

240971

PDB entries from 2025-08-27

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