4G3D

Crystal structure of human NF-kappaB inducing kinase (NIK)

Summary for 4G3D

• Entry DOI: 10.2210/pdb4g3d/pdb
• Related: 4G3C 4G3E 4G3F 4G3G
• Descriptor: NF-kappa-beta-inducing kinase, MAGNESIUM ION (3 entities in total)
• Functional Keywords: non-rd kinase, protein serine/threonine kinase, nf-kappab, map3k14, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q99558
• Total number of polymer chains: 4
• Total formula weight: 162922.49

Authors

Hymowitz, S.G.,de Leon-Boenig, G. (deposition date: 2012-07-13, release date: 2012-08-15, Last modification date: 2024-02-28)

• Primary citation: de Leon-Boenig, G.,Bowman, K.K.,Feng, J.A.,Crawford, T.,Everett, C.,Franke, Y.,Oh, A.,Stanley, M.,Staben, S.T.,Starovasnik, M.A.,Wallweber, H.J.,Wu, J.,Wu, L.C.,Johnson, A.R.,Hymowitz, S.G.; The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.; Structure, 20:1704-1714, 2012; PubMed: 22921830; DOI: 10.1016/j.str.2012.07.013

Experimental method

X-RAY DIFFRACTION (2.9 Å)