4FRW

Crystal structure of human nectin-4 extracellular fragment D1-D2

Summary for 4FRW

Entry DOI	10.2210/pdb4frw/pdb
Related	4FMF 4FMK 4FN0 4FOM 4FQP 4FS0
Descriptor	Poliovirus receptor-related protein 4 (1 entity in total)
Functional Keywords	immunoglobulin-like domain, ig domain, viral entry receptor, cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type I membrane protein (Potential). Processed poliovirus receptor-related protein 4: Secreted: Q96NY8
Total number of polymer chains	6
Total formula weight	140797.21
Authors	Harrison, O.J.,Jin, X.,Brasch, J.,Shapiro, L. (deposition date: 2012-06-26, release date: 2012-08-22, Last modification date: 2023-09-13)
Primary citation	Harrison, O.J.,Vendome, J.,Brasch, J.,Jin, X.,Hong, S.,Katsamba, P.S.,Ahlsen, G.,Troyanovsky, R.B.,Troyanovsky, S.M.,Honig, B.,Shapiro, L. Nectin ectodomain structures reveal a canonical adhesive interface. Nat.Struct.Mol.Biol., 19:906-915, 2012 Cited by PubMed: 22902367 DOI: 10.1038/nsmb.2366 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation