4FMO

Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of exo1

Summary for 4FMO

Entry DOI	10.2210/pdb4fmo/pdb
Related	4E4W 4FMN
Descriptor	DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ... (6 entities in total)
Functional Keywords	mismatch repair, mutl, endonuclease, zn-binding protein, dna damage, dna repair, hydrolase
Biological source	Saccharomyces cerevisiae (yeast) More
Cellular location	Nucleus: P38920 P14242 Nucleus (Potential): P39875
Total number of polymer chains	3
Total formula weight	62372.62
Authors	Gueneau, E.,Legrand, P.,Charbonnier, J.B. (deposition date: 2012-06-18, release date: 2013-02-20, Last modification date: 2023-09-13)
Primary citation	Gueneau, E.,Dherin, C.,Legrand, P.,Tellier-Lebegue, C.,Gilquin, B.,Bonnesoeur, P.,Londino, F.,Quemener, C.,Le Du, M.H.,Marquez, J.A.,Moutiez, M.,Gondry, M.,Boiteux, S.,Charbonnier, J.B. Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat.Struct.Mol.Biol., 20:461-468, 2013 Cited by PubMed: 23435383 DOI: 10.1038/nsmb.2511 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.04 Å)

Structure validation