4FMO
Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of exo1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA mismatch repair protein MLH1 | polymer | 288 | 33239.1 | 1 | UniProt (P38920) Pfam (PF16413) | Saccharomyces cerevisiae (yeast) | MutL protein homolog 1, Post meiotic segregation protein 2 |
| 2 | B (B) | DNA mismatch repair protein PMS1 | polymer | 240 | 27948.2 | 1 | UniProt (P14242) Pfam (PF08676) | Saccharomyces cerevisiae (yeast) | Postmeiotic segregation protein 1 |
| 3 | C (C) | DNA repair peptide | polymer | 8 | 1030.2 | 1 | UniProt (P39875) | Saccharomyces cerevisiae | Exodeoxyribonuclease I, EXO I, Exonuclease I, Protein DHS1 |
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A: 485 - 769 (UniProt: P38920)
B: 635 - 873 (UniProt: P14242)
| PDB | External Database | Details |
|---|---|---|
| Gly 482 | - | expression tag |
| Ala 483 | - | expression tag |
| Met 484 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 634 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62217.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 62372.6 |
