4FL2
Structural and Biophysical Characterization of the Syk Activation Switch
Summary for 4FL2
Entry DOI | 10.2210/pdb4fl2/pdb |
Related | 4FL1 4FL3 |
Descriptor | Tyrosine-protein kinase SYK, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | transferase, protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane (Probable): P43405 |
Total number of polymer chains | 1 |
Total formula weight | 72752.73 |
Authors | Graedler, U.,Schwarz, D.,Dresing, V.,Musil, M.,Bomke, J.,Frech, M.,Jaekel, S.,Rysiok, T.,Mueller-Pompalla, D.,Wegener, A. (deposition date: 2012-06-14, release date: 2012-11-28, Last modification date: 2024-02-28) |
Primary citation | Gradler, U.,Schwarz, D.,Dresing, V.,Musil, D.,Bomke, J.,Frech, M.,Greiner, H.,Jakel, S.,Rysiok, T.,Muller-Pompalla, D.,Wegener, A. Structural and biophysical characterization of the syk activation switch. J.Mol.Biol., 425:309-333, 2013 Cited by PubMed: 23154170DOI: 10.1016/j.jmb.2012.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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