4FKX

Crystal structure of nucleoside diphosphate kinase B from Trypanosoma brucei bound to CDP

4FKX の概要

• エントリーDOI: 10.2210/pdb4fkx/pdb
• 関連するPDBエントリー: 4F36 4F4A 4FKY
• 分子名称: Nucleoside diphosphate kinase, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, ntp biosynthesis, ndp, african trypanosomiasis, african sleeping sickness, transferase
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 55131.90

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-06-13, 公開日: 2012-06-27, 最終更新日: 2026-03-18)

• 主引用文献: Makori, P.,Boeckman, M.P.,David, H.S.,Payne, F.,Gatling, M.,Greer, C.,Hayes, D.,Jefferson, A.,Maxwell, M.,Smith, C.,Watson, J.,Williams, L.,Barkley, J.,Pepper, C.,Zininga, T.,Subramanian, S.,Abramov, A.,Gardberg, A.S.,Edwards, T.E.,Staker, B.L.,Stewart, L.J.,Myler, P.J.,Asojo, O.A.,Jeje, O.,Fanucchi, S.,Achilonu, I.,Smith, C.L.,Chakafana, G.; Structural and Functional Analyses of Trypanosoma brucei Nucleoside Diphosphate Kinase; Acs Omega, 2026; DOI: 10.1021/acsomega.5c11614

実験手法

X-RAY DIFFRACTION (1.7 Å)