4FKX

Crystal structure of nucleoside diphosphate kinase B from Trypanosoma brucei bound to CDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Nucleoside diphosphate kinase	polymer	161	17910.4	3	UniProt (Q381H3) Pfam (PF00334)	Trypanosoma brucei brucei	NDK B
2	D, F, I (A, B, C)	CYTIDINE-5'-DIPHOSPHATE	non-polymer		403.2	3	Chemie (CDP)
3	E, G, J (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H (B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
5	K, L, M (A, B, C)	water	water		18.0	516	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 153 (UniProt: Q381H3)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53731.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1400.6
All*	Total formula weight	55131.9

*Water molecules are not included.