4FFB

A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase

4FFB の概要

• エントリーDOI: 10.2210/pdb4ffb/pdb
• 分子名称: Tubulin alpha-1 chain, Tubulin beta chain, Protein STU2, ... (5 entities in total)
• 機能のキーワード: tubulin fold, heat repeats, cytoskeleton, microtubule, tubulin, tog domain, hydrolase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: P09733 P02557; Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body: P46675
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 134525.50

構造登録者

Ayaz, P.,Ye, X.,Huddleston, P.,Brautigam, C.A.,Rice, L.M. (登録日: 2012-05-31, 公開日: 2012-08-15, 最終更新日: 2023-09-13)

• 主引用文献: Ayaz, P.,Ye, X.,Huddleston, P.,Brautigam, C.A.,Rice, L.M.; A TOG: alpha beta-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase.; Science, 337:857-860, 2012; PubMed: 22904013; DOI: 10.1126/science.1221698

実験手法

X-RAY DIFFRACTION (2.882 Å)