4FBW
Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site
Summary for 4FBW
Entry DOI | 10.2210/pdb4fbw/pdb |
Related | 4fbk 4fbq 4FCX |
Descriptor | DNA repair protein rad32, DNA repair and telomere maintenance protein nbs1, MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | dna double-strand break repair, nuclease, hydrolase, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Schizosaccharomyces pombe (Fission yeast) More |
Cellular location | Nucleus : Q09683 O43070 |
Total number of polymer chains | 4 |
Total formula weight | 108937.83 |
Authors | Schiller, C.B.,Lammens, K.,Hopfner, K.P. (deposition date: 2012-05-23, release date: 2012-06-20, Last modification date: 2024-02-28) |
Primary citation | Schiller, C.B.,Lammens, K.,Guerini, I.,Coordes, B.,Feldmann, H.,Schlauderer, F.,Mockel, C.,Schele, A.,Strasser, K.,Jackson, S.P.,Hopfner, K.P. Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling. Nat.Struct.Mol.Biol., 19:693-700, 2012 Cited by PubMed: 22705791DOI: 10.1038/nsmb.2323 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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