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4FBW

Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA repair protein rad32polymer41747382.32UniProt (Q09683)
Pfam (PF00149)
Pfam (PF04152)
Schizosaccharomyces pombe (Fission yeast)
2C, D
(C, D)
DNA repair and telomere maintenance protein nbs1polymer596976.82UniProt (O43070)Schizosaccharomyces pombe (Fission yeast)
3E, F, G, H
(A, B)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
4I, J, K
(A, B, C)
waterwater18.0208Chemie (HOH)
Sequence modifications
A, B: 7 - 413 (UniProt: Q09683)
PDBExternal DatabaseDetails
Gly 5-expression tag
Pro 6-expression tag
Val 414-cloning artifact
Asp 415-cloning artifact
Glu 416-cloning artifact
Asn 417-cloning artifact
Leu 418-cloning artifact
Tyr 419-cloning artifact
Phe 420-cloning artifact
Gln 421-cloning artifact
C, D: 474 - 531 (UniProt: O43070)
PDBExternal DatabaseDetails
Gly 473-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight108718.1
Non-Polymers*Number of molecules4
Total formula weight219.8
All*Total formula weight108937.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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