4FAO

Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex

4FAO の概要

• エントリーDOI: 10.2210/pdb4fao/pdb
• 分子名称: Growth/differentiation factor 2, Serine/threonine-protein kinase receptor R3, Activin receptor type-2B, ... (5 entities in total)
• 機能のキーワード: tgf-beta, ctk, cystine knot, extracellular domain, receptor, signaling protein-signaling protein complex, signaling protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 36
• 化学式量合計: 459216.20

構造登録者

Townson, S.A.,Martinez-Hackert, E.,Greppi, C.,Lowden, P.,Sako, D.,Liu, J.,Ucran, J.A.,Liharska, K.,Underwood, K.W.,Seehra, J.,Kumar, R.,Grinberg, A.V. (登録日: 2012-05-22, 公開日: 2012-06-20, 最終更新日: 2024-04-03)

• 主引用文献: Townson, S.A.,Martinez-Hackert, E.,Greppi, C.,Lowden, P.,Sako, D.,Liu, J.,Ucran, J.A.,Liharska, K.,Underwood, K.W.,Seehra, J.,Kumar, R.,Grinberg, A.V.; Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex.; J.Biol.Chem., 287:27313-27325, 2012; PubMed: 22718755; DOI: 10.1074/jbc.M112.377960

実験手法

X-RAY DIFFRACTION (3.357 Å)