4F97

Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP and validoxylamine A 7'-phosphate

Summary for 4F97

• Entry DOI: 10.2210/pdb4f97/pdb
• Related: 3VDM 3VDN 4F96 4F9F
• Descriptor: VldE, GUANOSINE-5'-DIPHOSPHATE, [(1R,2R,3S,4S,5S)-2,3,4-TRIHYDROXY-5-{[(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}CYCLOHEXYL]METHYL DIHYDROGEN PHOSPHATE, ... (6 entities in total)
• Functional Keywords: twin rossman fold, transferase
• Biological source: Streptomyces hygroscopicus subsp. limoneus
• Total number of polymer chains: 2
• Total formula weight: 111925.17

Authors

Cavalier, M.C.,Yim, Y.-S.,Asamizu, S.,Neau, D.,Almabruk, K.H.,Mahmud, T.,Lee, Y.-H. (deposition date: 2012-05-18, release date: 2012-10-17, Last modification date: 2024-02-28)

• Primary citation: Cavalier, M.C.,Yim, Y.S.,Asamizu, S.,Neau, D.,Almabruk, K.H.,Mahmud, T.,Lee, Y.H.; Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex.; Plos One, 7:e44934-e44934, 2012; PubMed: 23028689; DOI: 10.1371/journal.pone.0044934

Experimental method

X-RAY DIFFRACTION (2.108 Å)