4MLL
The 1.4 A structure of the class D beta-lactamase OXA-1 K70D complexed with oxacillin
Replaces: 4F7YSummary for 4MLL
Entry DOI | 10.2210/pdb4mll/pdb |
Related | 4F94 |
Descriptor | Beta-lactamase OXA-1, (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, oxacillinase, antibiotic resistance, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 115220.08 |
Authors | June, C.M.,Vallier, B.C.,Bonomo, R.A.,Leonard, D.A.,Powers, R.A. (deposition date: 2013-09-06, release date: 2013-10-09, Last modification date: 2023-09-20) |
Primary citation | June, C.M.,Vallier, B.C.,Bonomo, R.A.,Leonard, D.A.,Powers, R.A. Structural Origins of Oxacillinase Specificity in Class D beta-Lactamases. Antimicrob.Agents Chemother., 58:333-341, 2014 Cited by PubMed: 24165180DOI: 10.1128/AAC.01483-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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