4MLL

The 1.4 A structure of the class D beta-lactamase OXA-1 K70D complexed with oxacillin

Replaces:  4F7Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Beta-lactamase OXA-1	polymer	251	28146.7	4	UniProt (P13661) Pfam (PF00905)	Escherichia coli	Penicillinase
2	E, J, L, O (A, B, C, D)	(2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid	non-polymer		403.5	4	Chemie (1S6)
3	F, G, H, K, M... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	7	Chemie (PO4)
4	I, Q, R (A, D)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	3	Chemie (MPD)
5	S, T, U, V (A, B, C, D)	water	water		18.0	945	Chemie (HOH)

Sequence modifications

A, B, C, D: 18 - 274 (UniProt: P13661)

PDB	External Database	Details
Asp 70	Lys 74	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	112587.0
Non-Polymers*	Number of molecules	14
	Total formula weight	2633.1
All*	Total formula weight	115220.1

*Water molecules are not included.