4MLL
The 1.4 A structure of the class D beta-lactamase OXA-1 K70D complexed with oxacillin
Replaces: 4F7YEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase OXA-1 | polymer | 251 | 28146.7 | 4 | UniProt (P13661) Pfam (PF00905) | Escherichia coli | Penicillinase |
| 2 | E, J, L, O (A, B, C, D) | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid | non-polymer | 403.5 | 4 | Chemie (1S6) | |||
| 3 | F, G, H, K, M... (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 4 | I, Q, R (A, D) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 5 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 945 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 18 - 274 (UniProt: P13661)
| PDB | External Database | Details |
|---|---|---|
| Asp 70 | Lys 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112587.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2633.1 | |
| All* | Total formula weight | 115220.1 |
