4F76

Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6 substrate

Summary for 4F76

• Entry DOI: 10.2210/pdb4f76/pdb
• Related: 4F73 4F74 4F75
• Descriptor: Protease, N terminal product of substrate p1-p6, C terminal product of substrate p1-p6, ... (4 entities in total)
• Functional Keywords: hiv-1 protease, substrate complex, aids, product complex, aspartyl protease, hydrolase, hydrolase-hydrolase product complex, hydrolase/hydrolase product
• Biological source: HIV-1 M:B_ARV2/SF2 (HIV-1); More
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
• Total number of polymer chains: 4
• Total formula weight: 22794.87

Authors

Schiffer, C.A.,Nalam, M.N.L.,Mittal, S. (deposition date: 2012-05-15, release date: 2013-05-15, Last modification date: 2024-02-28)

• Primary citation: Mittal, S.,Nalam, M.N.L.,Schiffer, C.A.; Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6 substrate; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)