4F76
Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6 substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10801.8 | 2 | UniProt (P03369) Pfam (PF00077) | HIV-1 M:B_ARV2/SF2 (HIV-1) | |
| 2 | C (C) | N terminal product of substrate p1-p6 | polymer | 5 | 590.7 | 1 | Human immunodeficiency virus 1 | ||
| 3 | D (D) | C terminal product of substrate p1-p6 | polymer | 5 | 600.7 | 1 | Human immunodeficiency virus 1 | ||
| 4 | E, F, G (A, B, C) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 497 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22794.9 | |
| All* | Total formula weight | 22794.9 |
