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4F60

Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (T148L, G171Q, A172V, C176F).

Summary for 4F60
Entry DOI10.2210/pdb4f60/pdb
DescriptorHaloalkane dehalogenase, FLUORIDE ION (3 entities in total)
Functional Keywordsmutation in access tunnel, hydrolase
Biological sourceRhodococcus rhodochrous
Total number of polymer chains1
Total formula weight34285.08
Authors
Plevaka, M.,Kuta-Smatanova, I.,Rezacova, P. (deposition date: 2012-05-14, release date: 2013-01-23, Last modification date: 2023-09-13)
Primary citationKoudelakova, T.,Chaloupkova, R.,Brezovsky, J.,Prokop, Z.,Sebestova, E.,Hesseler, M.,Khabiri, M.,Plevaka, M.,Kulik, D.,Kuta Smatanova, I.,Rezacova, P.,Ettrich, R.,Bornscheuer, U.T.,Damborsky, J.
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Angew.Chem.Int.Ed.Engl., 52:1959-1963, 2013
Cited by
PubMed: 23303607
DOI: 10.1002/anie.201206708
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

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