4F60
Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (T148L, G171Q, A172V, C176F).
Summary for 4F60
Entry DOI | 10.2210/pdb4f60/pdb |
Descriptor | Haloalkane dehalogenase, FLUORIDE ION (3 entities in total) |
Functional Keywords | mutation in access tunnel, hydrolase |
Biological source | Rhodococcus rhodochrous |
Total number of polymer chains | 1 |
Total formula weight | 34285.08 |
Authors | Plevaka, M.,Kuta-Smatanova, I.,Rezacova, P. (deposition date: 2012-05-14, release date: 2013-01-23, Last modification date: 2023-09-13) |
Primary citation | Koudelakova, T.,Chaloupkova, R.,Brezovsky, J.,Prokop, Z.,Sebestova, E.,Hesseler, M.,Khabiri, M.,Plevaka, M.,Kulik, D.,Kuta Smatanova, I.,Rezacova, P.,Ettrich, R.,Bornscheuer, U.T.,Damborsky, J. Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel. Angew.Chem.Int.Ed.Engl., 52:1959-1963, 2013 Cited by PubMed: 23303607DOI: 10.1002/anie.201206708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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