4F5C
Crystal structure of the spike receptor binding domain of a porcine respiratory coronavirus in complex with the pig aminopeptidase N ectodomain
Summary for 4F5C
Entry DOI | 10.2210/pdb4f5c/pdb |
Related | 4F2M |
Descriptor | Aminopeptidase N, PRCV spike protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | virus entry, cellular receptor, aminopeptidase n, glycosylation, virus membrane, metalloprotease, hydrolase-viral protein complex, hydrolase/viral protein |
Biological source | Sus scrofa (pig) More |
Total number of polymer chains | 4 |
Total formula weight | 320353.89 |
Authors | Santiago, C.,Reguera, J.,Gaurav, M.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M. (deposition date: 2012-05-13, release date: 2012-08-22, Last modification date: 2020-07-29) |
Primary citation | Reguera, J.,Santiago, C.,Mudgal, G.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M. Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies. Plos Pathog., 8:e1002859-e1002859, 2012 Cited by PubMed: 22876187DOI: 10.1371/journal.ppat.1002859 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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