4F2O

Quisqualate bound to the D655A mutant of the ligand binding domain of GluA3

4F2O の概要

• エントリーDOI: 10.2210/pdb4f2o/pdb
• 関連するPDBエントリー: 4F1Y 4F22 4F29 4F2Q 4F31 4F39 4F3B 4F3G
• 分子名称: Glutamate receptor 3, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ZINC ION, ... (4 entities in total)
• 機能のキーワード: glutamate receptor, glua3, glur3, ampa receptor, s1s2, lbd, neurotransmitter receptor, quisqualate, transport protein-agonist complex, transport protein/agonist
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : P19492
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29180.93

構造登録者

Ahmed, A.H.,Oswald, R.E. (登録日: 2012-05-08, 公開日: 2012-05-23, 最終更新日: 2023-09-13)

• 主引用文献: Holley, S.M.,Ahmed, A.H.,Srinivasan, J.,Murthy, S.E.,Weiland, G.A.,Oswald, R.E.,Nowak, L.M.; The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.; Biochemistry, 51:4015-4027, 2012; PubMed: 22512472; DOI: 10.1021/bi3001837

実験手法

X-RAY DIFFRACTION (1.912 Å)