4F2A

Crystal structure of cholestryl esters transfer protein in complex with inhibitors

4F2A の概要

• エントリーDOI: 10.2210/pdb4f2a/pdb
• 関連するPDBエントリー: 4EWS
• 分子名称: Cholesteryl ester transfer protein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTERYL OLEATE, ... (7 entities in total)
• 機能のキーワード: cholestryl ester transfer protein, high-density lipoprotein, low-density lipoprotein, cholestryl ester transfer protein-inhibitor complex, lipid transport-inhibitor complex, lipid transport/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56673.26

構造登録者

Liu, S.,Qiu, X. (登録日: 2012-05-07, 公開日: 2012-09-05, 最終更新日: 2020-07-29)

• 主引用文献: Liu, S.,Mistry, A.,Reynolds, J.M.,Lloyd, D.B.,Griffor, M.C.,Perry, D.A.,Ruggeri, R.B.,Clark, R.W.,Qiu, X.; Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.; J.Biol.Chem., 287:37321-37329, 2012; PubMed: 22961980; DOI: 10.1074/jbc.M112.380063

実験手法

X-RAY DIFFRACTION (3.11 Å)