4F1W

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine

Summary for 4F1W

• Entry DOI: 10.2210/pdb4f1w/pdb
• Related: 4F2P 4F2W
• Descriptor: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TRIETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: l-methionine biosynthetic process from s-adenosylmethionine, l-methionine salvage from methylthioadenosine, 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase, adenosylhomocysteine nucleosidase activity, methylthioadenosine nucleosidase activity, hydrolase activity, acting on glycosyl bonds, hydrolase
• Biological source: Salmonella enterica subsp. enterica serovar Choleraesuis
• Total number of polymer chains: 2
• Total formula weight: 54357.07

Authors

Haapalainen, A.M.,Thomas, K.,Bonanno, J.B.,Almo, S.C.,Schramm, V.L. (deposition date: 2012-05-07, release date: 2013-05-01, Last modification date: 2023-09-13)

• Primary citation: Haapalainen, A.M.,Thomas, K.,Tyler, P.C.,Evans, G.B.,Almo, S.C.,Schramm, V.L.; Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine; Structure, 21:963-974, 2013; PubMed: 23685211; DOI: 10.1016/j.str.2013.04.009

Experimental method

X-RAY DIFFRACTION (1.36 Å)