4F1W
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PGE A 301 |
| Chain | Residue |
| A | ASN153 |
| A | EDO309 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 A 302 |
| Chain | Residue |
| A | HIS65 |
| A | HOH560 |
| B | GLU64 |
| B | ASP200 |
| B | PHE210 |
| B | PGE302 |
| B | HOH520 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 303 |
| Chain | Residue |
| A | EDO309 |
| A | HOH453 |
| A | HOH582 |
| A | HOH597 |
| B | PHE105 |
| B | PRO113 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | GLU64 |
| A | LYS67 |
| A | PHE185 |
| A | EDO305 |
| A | HOH488 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | LYS67 |
| A | EDO304 |
| B | SER82 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 307 |
| Chain | Residue |
| A | GLU135 |
| A | HOH509 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | ARG17 |
| A | ASP18 |
| A | ARG23 |
| B | ARG142 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | PHE151 |
| A | SER196 |
| A | ASP197 |
| A | PGE301 |
| A | PG4303 |
| A | HOH537 |
| A | HOH597 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 310 |
| Chain | Residue |
| A | GLY87 |
| A | ILE89 |
| A | VAL213 |
| A | ALA214 |
| A | GLN217 |
| A | HOH538 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADE B 301 |
| Chain | Residue |
| B | SER76 |
| B | ALA77 |
| B | GLY78 |
| B | ALA150 |
| B | PHE151 |
| B | ILE152 |
| B | VAL171 |
| B | GLU172 |
| B | MET173 |
| B | SER196 |
| B | ASP197 |
| B | HOH429 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE B 302 |
| Chain | Residue |
| A | LEU28 |
| A | PG4302 |
| B | GLU64 |
| B | LYS67 |
| B | PHE185 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGE B 303 |
| Chain | Residue |
| B | MET9 |
| B | ILE50 |
| B | ASP208 |
| B | HOH442 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PG4 B 304 |
| Chain | Residue |
| A | LYS216 |
| B | ILE20 |
| B | ASP21 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| B | ALA81 |
| B | PRO166 |
| B | ASP167 |
| B | ALA168 |
