4F1H

Crystal structure of TDP2 from Danio rerio complexed with a single strand DNA

Summary for 4F1H

• Entry DOI: 10.2210/pdb4f1h/pdb
• Related: 4F1I 4FPV 4FVA 4GEW
• Descriptor: DNA (5'-D(P*TP*GP*CP*AP*G)-3'), Tyrosyl-DNA phosphodiesterase 2, PHOSPHATE ION, ... (7 entities in total)
• Functional Keywords: 5'-tyrosyl dna phosphodiesterase, hydrolase-dna complex, hydrolase/dna
• Biological source: Danio rerio (leopard danio,zebra danio,zebra fish); More
• Cellular location: Nucleus (By similarity): Q5XJA0 Q5XJA0
• Total number of polymer chains: 3
• Total formula weight: 59106.25

Authors

Shi, K.,Kurahashi, K.,Aihara, H. (deposition date: 2012-05-06, release date: 2012-10-31, Last modification date: 2024-02-28)

• Primary citation: Shi, K.,Kurahashi, K.,Gao, R.,Tsutakawa, S.E.,Tainer, J.A.,Pommier, Y.,Aihara, H.; Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.; Nat.Struct.Mol.Biol., 19:1372-1377, 2012; PubMed: 23104058; DOI: 10.1038/nsmb.2423

Experimental method

X-RAY DIFFRACTION (1.662 Å)