4EXY

Crystal structure of NDM-1 bound to ethylene glycol

Summary for 4EXY

• Entry DOI: 10.2210/pdb4exy/pdb
• Related: 3Q6X 3SPU 4EXS 4EY2 4EYB 4EYF 4EYL
• Descriptor: Beta-lactamase NDM-1, 1,2-ETHANEDIOL, ZINC ION, ... (4 entities in total)
• Functional Keywords: metallo-beta-lactamase, antibiotic, hydrolase
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm : C7C422
• Total number of polymer chains: 2
• Total formula weight: 57865.20

Authors

Strynadka, N.C.J.,King, D.T. (deposition date: 2012-05-01, release date: 2012-08-08, Last modification date: 2024-02-28)

• Primary citation: King, D.T.,Worrall, L.J.,Gruninger, R.,Strynadka, N.C.; New Delhi Metallo-Beta-Lactamase: Structural Insights into Beta-Lactam Recognition and Inhibition; J.Am.Chem.Soc., 134:11362-11365, 2012; PubMed: 22713171; DOI: 10.1021/ja303579d

Experimental method

X-RAY DIFFRACTION (1.47 Å)