4EWE
Study on structure and function relationships in human Pirin with Manganese ion
Summary for 4EWE
Entry DOI | 10.2210/pdb4ewe/pdb |
Related | 4ERO 4EWA 4EWB 4EWD |
Descriptor | Pirin, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | beta sandwich, cupin, metal binding protein, transcription cofactor activity, protein binding, nucleus, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : O00625 |
Total number of polymer chains | 1 |
Total formula weight | 32462.60 |
Authors | Liu, F.,Rehmani, I.,Fu, R.,Esaka, S.,Chen, L.,Serrano, V.,Liu, A. (deposition date: 2012-04-26, release date: 2013-05-29, Last modification date: 2024-02-28) |
Primary citation | Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A. Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013 Cited by PubMed: 23716661DOI: 10.1073/pnas.1221743110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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