4EWA

Study on structure and function relationships in human Pirin with Fe ion

Summary for 4EWA

• Entry DOI: 10.2210/pdb4ewa/pdb
• Related: 4ERO 4EWB 4EWD 4EWE
• Descriptor: Pirin, FE (III) ION (3 entities in total)
• Functional Keywords: beta sandwich, cupin, iron, metal binding protein, transcription cofactor activity, protein binding, nucleus, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O00625
• Total number of polymer chains: 1
• Total formula weight: 32215.24

Authors

Liu, F.,Rehmani, I.,Chen, L.,Fu, R.,Serrano, V.,Wilson, D.W.,Liu, A. (deposition date: 2012-04-26, release date: 2013-05-29, Last modification date: 2023-09-13)

• Primary citation: Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A.; Pirin is an iron-dependent redox regulator of NF-kappa B.; Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013; PubMed: 23716661; DOI: 10.1073/pnas.1221743110

Experimental method

X-RAY DIFFRACTION (2.47 Å)