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4EQ1

Crystal Structure of the ARNT PAS-B homodimer

Summary for 4EQ1
Entry DOI10.2210/pdb4eq1/pdb
Related1X0O 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82
DescriptorAryl hydrocarbon receptor nuclear translocator, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL (3 entities in total)
Functional Keywordsper-arnt-sim, transcription regulation, homodimer, transcription factor, dna-binding, hif1, hif2, ahr, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P27540
Total number of polymer chains2
Total formula weight26099.60
Authors
Gardner, K.H.,Key, J.M. (deposition date: 2012-04-17, release date: 2013-04-17, Last modification date: 2023-09-13)
Primary citationGuo, Y.,Partch, C.L.,Key, J.,Card, P.B.,Pashkov, V.,Patel, A.,Bruick, R.K.,Wurdak, H.,Gardner, K.H.
Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules.
Acs Chem.Biol., 8:626-635, 2013
Cited by
PubMed: 23240775
DOI: 10.1021/cb300604u
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

数据于2024-03-27公开中

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